1. Medical treatment (light therapy)
Inada et al. irradiated Jurkat tumor cells with ultraviolet LED (365 nm). Through comparison, the number of apoptosis and necrosis after irradiation with UV LED and traditional light source system is approximately the same. This proves that UV LEDs have the potential and possibility of being a new light source for phototherapy, and can replace traditional UV fluorescent lamps that are bulky, short-lived, and consume more energy.
2. Fluorescence detection (biological detection)
In the fluorescence detection, continuous UV light excitation is difficult to provide periodic response, cannot form a clear fluorescence analysis image, and the fluorescence intensity of organic matter decays with exposure time. Huang et al. used an adjustable pulse control module to realize organic dyes. Fluorescence test of BL-ORT. The system structure is shown in the figure below. The adjustable range of the pulse control module's period is 1~1 000 ms, which is used to improve the stability of the power supply and the uniformity of the light source radiation. The LED module uses 6 3W 405 nm UVCLEDs and 6 3 W 375 nm UV-LEDs for fluorescence detection, and is equipped with 3 white light LEDs to provide general illumination of visible images. When BL-ORT is excited by pulsed UV-LED light with a period of 30 ms, most of the complete fluorescence data can be obtained. Moreover, the energy consumption of this pulsed excitation light source can be reduced to 50%. The system can be used for fluorescence detection in biochemical reactions, security, industry, agriculture and other fields.
